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Ozonated water lavage and physiological saline irrigation combined with vacuum-sealed drainage in the treatment of 18 cases of chronic osteomyelitis

OBJECTIVE: Ozone is a colorless gas used as a disinfectant and to treat diseases by limiting the effects of bacteria, viruses, fungi, yeast, and protozoa. In this study, we investigated the clinical efficacy of ozonated water lavage and physiological saline irrigation combined with vacuum-sealed dra...

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Autores principales: Yasheng, Tayierjiang, Mijiti, Aini, Yushan, Maimaiaili, Liu, Zhenhui, Liu, Yanshi, Yusufu, Aihemaitijiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020234/
https://www.ncbi.nlm.nih.gov/pubmed/33784843
http://dx.doi.org/10.1177/0300060521999530
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author Yasheng, Tayierjiang
Mijiti, Aini
Yushan, Maimaiaili
Liu, Zhenhui
Liu, Yanshi
Yusufu, Aihemaitijiang
author_facet Yasheng, Tayierjiang
Mijiti, Aini
Yushan, Maimaiaili
Liu, Zhenhui
Liu, Yanshi
Yusufu, Aihemaitijiang
author_sort Yasheng, Tayierjiang
collection PubMed
description OBJECTIVE: Ozone is a colorless gas used as a disinfectant and to treat diseases by limiting the effects of bacteria, viruses, fungi, yeast, and protozoa. In this study, we investigated the clinical efficacy of ozonated water lavage and physiological saline irrigation combined with vacuum-sealed drainage (VSD) in the treatment of chronic osteomyelitis. METHODS: Eighteen patients (14 men and 4 women) with chronic osteomyelitis in the limbs (tibia: 13 cases; femur: 4 cases; humerus: 1 case) admitted to our hospital between April 2012 and October 2018 were selected. The patients were aged 9 to 52 years, with a mean age of 31 years. All patients underwent ozonated water lavage and physiological saline irrigation combined with VSD negative pressure closed drainage during hospitalization. The patients were followed up for 18 to 84 months, with a mean of 31 months. RESULTS: Osteomyelitis recurred in only one case of nonunion. The length of hospitalization was 18 to 29 days, with a mean of 21 days. CONCLUSIONS: A combination of ozonated water lavage, physiological saline irrigation, and VSD provided good clinical effects in the treatment of chronic osteomyelitis, and thus, is recommended for such treatment.
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spelling pubmed-80202342021-04-16 Ozonated water lavage and physiological saline irrigation combined with vacuum-sealed drainage in the treatment of 18 cases of chronic osteomyelitis Yasheng, Tayierjiang Mijiti, Aini Yushan, Maimaiaili Liu, Zhenhui Liu, Yanshi Yusufu, Aihemaitijiang J Int Med Res Clinical Research Article OBJECTIVE: Ozone is a colorless gas used as a disinfectant and to treat diseases by limiting the effects of bacteria, viruses, fungi, yeast, and protozoa. In this study, we investigated the clinical efficacy of ozonated water lavage and physiological saline irrigation combined with vacuum-sealed drainage (VSD) in the treatment of chronic osteomyelitis. METHODS: Eighteen patients (14 men and 4 women) with chronic osteomyelitis in the limbs (tibia: 13 cases; femur: 4 cases; humerus: 1 case) admitted to our hospital between April 2012 and October 2018 were selected. The patients were aged 9 to 52 years, with a mean age of 31 years. All patients underwent ozonated water lavage and physiological saline irrigation combined with VSD negative pressure closed drainage during hospitalization. The patients were followed up for 18 to 84 months, with a mean of 31 months. RESULTS: Osteomyelitis recurred in only one case of nonunion. The length of hospitalization was 18 to 29 days, with a mean of 21 days. CONCLUSIONS: A combination of ozonated water lavage, physiological saline irrigation, and VSD provided good clinical effects in the treatment of chronic osteomyelitis, and thus, is recommended for such treatment. SAGE Publications 2021-03-30 /pmc/articles/PMC8020234/ /pubmed/33784843 http://dx.doi.org/10.1177/0300060521999530 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Clinical Research Article
Yasheng, Tayierjiang
Mijiti, Aini
Yushan, Maimaiaili
Liu, Zhenhui
Liu, Yanshi
Yusufu, Aihemaitijiang
Ozonated water lavage and physiological saline irrigation combined with vacuum-sealed drainage in the treatment of 18 cases of chronic osteomyelitis
title Ozonated water lavage and physiological saline irrigation combined with vacuum-sealed drainage in the treatment of 18 cases of chronic osteomyelitis
title_full Ozonated water lavage and physiological saline irrigation combined with vacuum-sealed drainage in the treatment of 18 cases of chronic osteomyelitis
title_fullStr Ozonated water lavage and physiological saline irrigation combined with vacuum-sealed drainage in the treatment of 18 cases of chronic osteomyelitis
title_full_unstemmed Ozonated water lavage and physiological saline irrigation combined with vacuum-sealed drainage in the treatment of 18 cases of chronic osteomyelitis
title_short Ozonated water lavage and physiological saline irrigation combined with vacuum-sealed drainage in the treatment of 18 cases of chronic osteomyelitis
title_sort ozonated water lavage and physiological saline irrigation combined with vacuum-sealed drainage in the treatment of 18 cases of chronic osteomyelitis
topic Clinical Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020234/
https://www.ncbi.nlm.nih.gov/pubmed/33784843
http://dx.doi.org/10.1177/0300060521999530
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