PCAT-1 facilitates breast cancer progression via binding to RACK1 and enhancing oxygen-independent stability of HIF-1α

Hypoxia induces a series of cellular adaptive responses that enable promotion of inflammation and cancer development. Hypoxia-inducible factor-1α (HIF-1α) is involved in the hypoxia response and cancer promotion, and it accumulates in hypoxia and is degraded under normoxic conditions. Here we identi...

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Detalles Bibliográficos
Autores principales: Wang, Jianlong, Chen, Xuyi, Hu, Haijuan, Yao, Mengting, Song, Yanbiao, Yang, Aimin, Xu, Xiuhua, Zhang, Ning, Gao, Jianzhao, Liu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020346/
https://www.ncbi.nlm.nih.gov/pubmed/33850635
http://dx.doi.org/10.1016/j.omtn.2021.02.034

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