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Voluntary wheel running complements microdystrophin gene therapy to improve muscle function in mdx mice

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We tested the hypothesis that voluntary wheel running would complement microdystrophin gene therapy to improve muscle function in young mdx mice, a model of Duchenne muscular dystrophy. mdx mice injected with a single dose of AAV9-CK8-microdystrophin or vehicle at age 7 weeks were assigned to three...

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Autores principales:	Hamm, Shelby E., Fathalikhani, Daniel D., Bukovec, Katherine E., Addington, Adele K., Zhang, Haiyan, Perry, Justin B., McMillan, Ryan P., Lawlor, Michael W., Prom, Mariah J., Vanden Avond, Mark A., Kumar, Suresh N., Coleman, Kirsten E., Dupont, J.B., Mack, David L., Brown, David A., Morris, Carl A., Gonzalez, J. Patrick, Grange, Robert W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020351/ https://www.ncbi.nlm.nih.gov/pubmed/33850950 http://dx.doi.org/10.1016/j.omtm.2021.02.024

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