Antiaging gene Klotho regulates epithelial-mesenchymal transition and increases sensitivity to pemetrexed by inducing lipocalin-2 expression

Epithelial-mesenchymal transition (EMT) is considered to serve an important role in the metastatic/invasive ability of cancer cells, in the acquisition of drug resistance, and in metabolic reprogramming. In the present study, it was hypothesized that the Klotho gene is involved in the metastatic/inv...

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Detalles Bibliográficos
Autores principales: Takegahara, Kyoshiro, Usuda, Jitsuo, Inoue, Tatsuya, Sonokawa, Takumi, Matsui, Takuma, Matsumoto, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020392/
https://www.ncbi.nlm.nih.gov/pubmed/33841579
http://dx.doi.org/10.3892/ol.2021.12679

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