Cargando…
Exposure to p40 in Early Life Prevents Intestinal Inflammation in Adulthood Through Inducing a Long-Lasting Epigenetic Imprint on TGFβ
BACKGROUND & AIMS: Colonization by gut microbiota in early life confers beneficial effects on immunity throughout the host’s lifespan. We sought to elucidate the mechanisms whereby neonatal supplementation with p40, a probiotic functional factor, reprograms intestinal epithelial cells for protec...
Autores principales: | Deng, Yilin, McDonald, Oliver G., Means, Anna L., Peek, Richard M., Washington, M. Kay, Acra, Sari A., Polk, D. Brent, Yan, Fang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020481/ https://www.ncbi.nlm.nih.gov/pubmed/33482393 http://dx.doi.org/10.1016/j.jcmgh.2021.01.004 |
Ejemplares similares
-
Neonatal Colonization of Mice with LGG Promotes Intestinal Development and Decreases Susceptibility to Colitis in Adulthood
por: Yan, Fang, et al.
Publicado: (2016) -
Supplementation of p40, a Lactobacillus rhamnosus GG-derived protein, in early life promotes epidermal growth factor receptor-dependent intestinal development and long-term health outcomes
por: Shen, Xi, et al.
Publicado: (2018) -
A LGG-derived protein promotes IgA production through up-regulation of APRIL expression in intestinal epithelial cells
por: Wang, Yang, et al.
Publicado: (2016) -
Identification of a functional peptide of a probiotic bacterium-derived protein for the sustained effect on preventing colitis
por: Kaur, Harpreet, et al.
Publicado: (2023) -
Epigenetic Mechanisms of Genomic Imprinting: Common Themes in the Regulation of Imprinted Regions in Mammals, Plants, and Insects
por: MacDonald, William A.
Publicado: (2012)