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Diverse and converging roles of ERK1/2 and ERK5 pathways on mesenchymal to epithelial transition in breast cancer
The epithelial to mesenchymal transition (EMT) is characterized by a loss of cell polarity, a decrease in the epithelial cell marker E-cadherin, and an increase in mesenchymal markers including the zinc-finger E-box binding homeobox (ZEB1). The EMT is also associated with an increase in cell migrati...
Autores principales: | Bhatt, Akshita B., Wright, Thomas D., Barnes, Van, Chakrabarty, Suravi, Matossian, Margarite D., Lexner, Erin, Ucar, Deniz A., Miele, Lucio, Flaherty, Patrick T., Burow, Matthew E., Cavanaugh, Jane E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020482/ https://www.ncbi.nlm.nih.gov/pubmed/33761370 http://dx.doi.org/10.1016/j.tranon.2021.101046 |
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