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Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age
Although the influence of advanced maternal age (AMA) and delayed childbearing on adverse maternal and perinatal outcomes has been studied extensively, no universal consensus on the definition of AMA exists. This terminology currently refers to the later years of a woman's reproductive life spa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020515/ https://www.ncbi.nlm.nih.gov/pubmed/33185505 http://dx.doi.org/10.1089/jwh.2020.8860 |
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author | Correa-de-Araujo, Rosaly Yoon, Sung Sug (Sarah) |
author_facet | Correa-de-Araujo, Rosaly Yoon, Sung Sug (Sarah) |
author_sort | Correa-de-Araujo, Rosaly |
collection | PubMed |
description | Although the influence of advanced maternal age (AMA) and delayed childbearing on adverse maternal and perinatal outcomes has been studied extensively, no universal consensus on the definition of AMA exists. This terminology currently refers to the later years of a woman's reproductive life span and generally applies to women age ≥35 years. AMA increases the risk of pregnancy complications, including ectopic pregnancy, spontaneous abortion, fetal chromosomal abnormalities, congenital anomalies, placenta previa and abruption, gestational diabetes, preeclampsia, and cesarean delivery. Such complications could be the cause of preterm birth and increase the risk of perinatal mortality. For women who have a chronic illness, pregnancy may lead to additional risk that demands increased monitoring or surveillance. The management of pregnant women of AMA requires understanding the relationship between age and preexisting comorbidities. The outcomes from pregnancy in AMA may have a negative impact on women's health as they age because of both the changes from the pregnancy itself and the increased risk of pregnancy-related complications. Postpartum depression affects women of AMA at higher rates. Links between preeclampsia and the risk of future development of cardiovascular disease require follow-up surveillance. The association between hypertensive pregnancy disorders and cognitive and brain functions needs further investigation of sex-specific risk factors across the life span. Educating providers and women of AMA is crucial to facilitate clinical decision making and such education should consider cultural influences, risk perception, and women's health literacy, as well as providers' biases and system issues. |
format | Online Article Text |
id | pubmed-8020515 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Mary Ann Liebert, Inc., publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-80205152021-04-06 Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age Correa-de-Araujo, Rosaly Yoon, Sung Sug (Sarah) J Womens Health (Larchmt) Special Issue Articles Although the influence of advanced maternal age (AMA) and delayed childbearing on adverse maternal and perinatal outcomes has been studied extensively, no universal consensus on the definition of AMA exists. This terminology currently refers to the later years of a woman's reproductive life span and generally applies to women age ≥35 years. AMA increases the risk of pregnancy complications, including ectopic pregnancy, spontaneous abortion, fetal chromosomal abnormalities, congenital anomalies, placenta previa and abruption, gestational diabetes, preeclampsia, and cesarean delivery. Such complications could be the cause of preterm birth and increase the risk of perinatal mortality. For women who have a chronic illness, pregnancy may lead to additional risk that demands increased monitoring or surveillance. The management of pregnant women of AMA requires understanding the relationship between age and preexisting comorbidities. The outcomes from pregnancy in AMA may have a negative impact on women's health as they age because of both the changes from the pregnancy itself and the increased risk of pregnancy-related complications. Postpartum depression affects women of AMA at higher rates. Links between preeclampsia and the risk of future development of cardiovascular disease require follow-up surveillance. The association between hypertensive pregnancy disorders and cognitive and brain functions needs further investigation of sex-specific risk factors across the life span. Educating providers and women of AMA is crucial to facilitate clinical decision making and such education should consider cultural influences, risk perception, and women's health literacy, as well as providers' biases and system issues. Mary Ann Liebert, Inc., publishers 2021-02-01 2021-02-02 /pmc/articles/PMC8020515/ /pubmed/33185505 http://dx.doi.org/10.1089/jwh.2020.8860 Text en © Rosaly Correa-de-Araujo et al. 2021; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are cited. |
spellingShingle | Special Issue Articles Correa-de-Araujo, Rosaly Yoon, Sung Sug (Sarah) Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age |
title | Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age |
title_full | Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age |
title_fullStr | Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age |
title_full_unstemmed | Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age |
title_short | Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age |
title_sort | clinical outcomes in high-risk pregnancies due to advanced maternal age |
topic | Special Issue Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020515/ https://www.ncbi.nlm.nih.gov/pubmed/33185505 http://dx.doi.org/10.1089/jwh.2020.8860 |
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