Cytomegalovirus proctitis as a complication of COVID-19 with immunosuppressive treatments

We report a case of reactivated biopsy-proven cytomegalovirus proctitis complicating the course of severe COVID-19 pneumonia treated with dexamethasone, anakinra and lopinavir/ritonavir. No other contributing factor was found than iatrogenic immunosuppression and COVID-19 immune dysregulation. We dr...

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Detalles Bibliográficos
Autores principales: Maillet, François, Pourbaix, Annabelle, le Pluart, Diane, Sirmai, Laura, Postolache, Speranta Andreea, Couvelard, Anne, Houhou-Fidouh, Nadhira, Males, Lisa, Deconinck, Laurène, Lescure, François-Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020601/
https://www.ncbi.nlm.nih.gov/pubmed/33842207
http://dx.doi.org/10.1016/j.idcr.2021.e01111
Descripción
Sumario:We report a case of reactivated biopsy-proven cytomegalovirus proctitis complicating the course of severe COVID-19 pneumonia treated with dexamethasone, anakinra and lopinavir/ritonavir. No other contributing factor was found than iatrogenic immunosuppression and COVID-19 immune dysregulation. We draw attention to the immunosuppressive risk when treating severe COVID-19 pneumonia with immunomodulators.

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