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Rapidly Growing Huge Lower Back Malignant Peripheral Nerve Sheath Tumour

Malignant peripheral nerve sheath tumours (also called neurofibrosarcomas) are a rare, highly aggressive soft tissue sarcomas that arise from the peripheral nerves or cells associated with the nerve sheath, such as Schwann cells, peri-neural cells and fibroblasts. It is representing 10% of all soft...

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Autores principales: Abuzarifa, Naim, Al-Chalabi, Muath Mamdouh Mahmod, Wan Sulaiman, Wan Azman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020617/
https://www.ncbi.nlm.nih.gov/pubmed/33842103
http://dx.doi.org/10.7759/cureus.13712
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author Abuzarifa, Naim
Al-Chalabi, Muath Mamdouh Mahmod
Wan Sulaiman, Wan Azman
author_facet Abuzarifa, Naim
Al-Chalabi, Muath Mamdouh Mahmod
Wan Sulaiman, Wan Azman
author_sort Abuzarifa, Naim
collection PubMed
description Malignant peripheral nerve sheath tumours (also called neurofibrosarcomas) are a rare, highly aggressive soft tissue sarcomas that arise from the peripheral nerves or cells associated with the nerve sheath, such as Schwann cells, peri-neural cells and fibroblasts. It is representing 10% of all soft tissue sarcomas in which it is considered as an extremely rare malignancy, especially in patients with neurofibromatosis type I. In the general population, it affects approximately 1 in 100,000 people. This article is reporting a 56-year-old Malay female patient who is a known case of neurofibromatosis type I for 20 years, presented with a lower back, pruritic, gradually increasing swelling during the last five months. Last month before the presentation, the lesion rapidly grows, reaching a size of (15×15 cm), accompanied by foul-smelling discharge and pain exacerbated with movement. Although no history of preceding trauma or accident, the mass bleeds within contact. In conclusion, only a few cases of giant malignant peripheral nerve sheath tumours reported in the literature describing its location and growth progression. We present a massive, extremely rapid growth of cutaneous exophytic malignant peripheral nerve sheath tumours over the lower back.
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spelling pubmed-80206172021-04-08 Rapidly Growing Huge Lower Back Malignant Peripheral Nerve Sheath Tumour Abuzarifa, Naim Al-Chalabi, Muath Mamdouh Mahmod Wan Sulaiman, Wan Azman Cureus Plastic Surgery Malignant peripheral nerve sheath tumours (also called neurofibrosarcomas) are a rare, highly aggressive soft tissue sarcomas that arise from the peripheral nerves or cells associated with the nerve sheath, such as Schwann cells, peri-neural cells and fibroblasts. It is representing 10% of all soft tissue sarcomas in which it is considered as an extremely rare malignancy, especially in patients with neurofibromatosis type I. In the general population, it affects approximately 1 in 100,000 people. This article is reporting a 56-year-old Malay female patient who is a known case of neurofibromatosis type I for 20 years, presented with a lower back, pruritic, gradually increasing swelling during the last five months. Last month before the presentation, the lesion rapidly grows, reaching a size of (15×15 cm), accompanied by foul-smelling discharge and pain exacerbated with movement. Although no history of preceding trauma or accident, the mass bleeds within contact. In conclusion, only a few cases of giant malignant peripheral nerve sheath tumours reported in the literature describing its location and growth progression. We present a massive, extremely rapid growth of cutaneous exophytic malignant peripheral nerve sheath tumours over the lower back. Cureus 2021-03-05 /pmc/articles/PMC8020617/ /pubmed/33842103 http://dx.doi.org/10.7759/cureus.13712 Text en Copyright © 2021, Abuzarifa et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Plastic Surgery
Abuzarifa, Naim
Al-Chalabi, Muath Mamdouh Mahmod
Wan Sulaiman, Wan Azman
Rapidly Growing Huge Lower Back Malignant Peripheral Nerve Sheath Tumour
title Rapidly Growing Huge Lower Back Malignant Peripheral Nerve Sheath Tumour
title_full Rapidly Growing Huge Lower Back Malignant Peripheral Nerve Sheath Tumour
title_fullStr Rapidly Growing Huge Lower Back Malignant Peripheral Nerve Sheath Tumour
title_full_unstemmed Rapidly Growing Huge Lower Back Malignant Peripheral Nerve Sheath Tumour
title_short Rapidly Growing Huge Lower Back Malignant Peripheral Nerve Sheath Tumour
title_sort rapidly growing huge lower back malignant peripheral nerve sheath tumour
topic Plastic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020617/
https://www.ncbi.nlm.nih.gov/pubmed/33842103
http://dx.doi.org/10.7759/cureus.13712
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