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The CysLT(2)R receptor mediates leukotriene C(4)-driven acute and chronic itch
Acute and chronic itch are burdensome manifestations of skin pathologies including allergic skin diseases and atopic dermatitis, but the underlying molecular mechanisms are not well understood. Cysteinyl leukotrienes (CysLTs), comprising LTC(4), LTD(4), and LTE(4), are produced by immune cells durin...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020753/ https://www.ncbi.nlm.nih.gov/pubmed/33753496 http://dx.doi.org/10.1073/pnas.2022087118 |