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A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment

The CXC chemokine receptor type 4 (CXCR4) receptor and its ligand, CXCL12, are overexpressed in various cancers and mediate tumor progression and hypoxia-mediated resistance to cancer therapy. While CXCR4 antagonists have potential anticancer effects when combined with conventional anticancer drugs,...

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Detalles Bibliográficos
Autores principales:	Song, Jen-Shin, Chang, Chih-Chun, Wu, Chien-Huang, Dinh, Trinh Kieu, Jan, Jiing-Jyh, Huang, Kuan-Wei, Chou, Ming-Chen, Shiue, Ting-Yun, Yeh, Kai-Chia, Ke, Yi-Yu, Yeh, Teng-Kuang, Ta, Yen-Nhi Ngoc, Lee, Chia-Jui, Huang, Jing-Kai, Sung, Yun-Chieh, Shia, Kak-Shan, Chen, Yunching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020795/ https://www.ncbi.nlm.nih.gov/pubmed/33753481 http://dx.doi.org/10.1073/pnas.2015433118

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