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COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities

The emergence of novel virus SARS-CoV-2 that causes COVID-19 has complicated Africa’s public health challenges, especially with the pre-existing epidemics such as HIV/AIDS. We highlight the known evidence related to COVID-19 infections among people with HIV (PWH) with specific reference to Africa. T...

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Autores principales: Essien, Ekere James, Mgbere, Osaro, Iloanusi, Sorochi, Abughosh, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Global Health and Education Projects, Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020823/
https://www.ncbi.nlm.nih.gov/pubmed/33842057
http://dx.doi.org/10.21106/ijma.461
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author Essien, Ekere James
Mgbere, Osaro
Iloanusi, Sorochi
Abughosh, Susan M.
author_facet Essien, Ekere James
Mgbere, Osaro
Iloanusi, Sorochi
Abughosh, Susan M.
author_sort Essien, Ekere James
collection PubMed
description The emergence of novel virus SARS-CoV-2 that causes COVID-19 has complicated Africa’s public health challenges, especially with the pre-existing epidemics such as HIV/AIDS. We highlight the known evidence related to COVID-19 infections among people with HIV (PWH) with specific reference to Africa. The knowledge gaps, level of public health preparedness and the potential research priorities are also outlined. Although the epidemiology and clinical course of COVID-19 in HIV patients are evolving, existing evidence indicate that the disease outcomes are comparable to that of the general population. However, PWH with low CD4 cell counts may have worse outcomes than individuals with restored immunity, whereas old age and co-morbidities such as obesity, hypertension and diabetes can further increase their overall risk. While there may be slight disruption of HIV service delivery in selected African countries, the resilience and resourcefulness of others have helped to sustain HIV service delivery and enhanced the level of public health preparedness and fight against the pandemic. The paucity of data and research studies on HIV-COVID-19 coinfection in Africa, call for concerted efforts to address these limitations.
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spelling pubmed-80208232021-04-08 COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities Essien, Ekere James Mgbere, Osaro Iloanusi, Sorochi Abughosh, Susan M. Int J MCH AIDS Commentary | Covid-19 and HIV/AIDS The emergence of novel virus SARS-CoV-2 that causes COVID-19 has complicated Africa’s public health challenges, especially with the pre-existing epidemics such as HIV/AIDS. We highlight the known evidence related to COVID-19 infections among people with HIV (PWH) with specific reference to Africa. The knowledge gaps, level of public health preparedness and the potential research priorities are also outlined. Although the epidemiology and clinical course of COVID-19 in HIV patients are evolving, existing evidence indicate that the disease outcomes are comparable to that of the general population. However, PWH with low CD4 cell counts may have worse outcomes than individuals with restored immunity, whereas old age and co-morbidities such as obesity, hypertension and diabetes can further increase their overall risk. While there may be slight disruption of HIV service delivery in selected African countries, the resilience and resourcefulness of others have helped to sustain HIV service delivery and enhanced the level of public health preparedness and fight against the pandemic. The paucity of data and research studies on HIV-COVID-19 coinfection in Africa, call for concerted efforts to address these limitations. Global Health and Education Projects, Inc 2021 2021-03-24 /pmc/articles/PMC8020823/ /pubmed/33842057 http://dx.doi.org/10.21106/ijma.461 Text en Copyright © 2021 Essien et al. https://creativecommons.org/licenses/by-nc-sa/3.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary | Covid-19 and HIV/AIDS
Essien, Ekere James
Mgbere, Osaro
Iloanusi, Sorochi
Abughosh, Susan M.
COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities
title COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities
title_full COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities
title_fullStr COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities
title_full_unstemmed COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities
title_short COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities
title_sort covid-19 infection among people with hiv/aids in africa: knowledge gaps, public health preparedness and research priorities
topic Commentary | Covid-19 and HIV/AIDS
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020823/
https://www.ncbi.nlm.nih.gov/pubmed/33842057
http://dx.doi.org/10.21106/ijma.461
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