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Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity

Tauopathies are neurodegenerative disorders with increasing incidence and still without cure. The extensive time required for development and approval of novel therapeutics highlights the need for testing and repurposing known safe molecules. Since doxycycline impacts α-synuclein aggregation and tox...

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Detalles Bibliográficos
Autores principales:	Medina, Luciana, González-Lizárraga, Florencia, Dominguez-Meijide, Antonio, Ploper, Diego, Parrales, Valeria, Sequeira, Sabrina, Cima-Omori, Maria-Sol, Zweckstetter, Markus, Del Bel, Elaine, Michel, Patrick P., Outeiro, Tiago Fleming, Raisman-Vozari, Rita, Chehín, Rosana, Socias, Sergio B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020845/ https://www.ncbi.nlm.nih.gov/pubmed/33828477 http://dx.doi.org/10.3389/fnagi.2021.635760

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