A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection

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Broadly neutralizing antibodies (bnAbs) to coronaviruses (CoVs) are valuable in their own right as prophylactic and therapeutic reagents to treat diverse CoVs and, importantly, as templates for rational pan-CoV vaccine design. We recently described a bnAb, CC40.8, from a coronavirus disease 2019 (CO...

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Detalles Bibliográficos
Autores principales: Zhou, Panpan, Yuan, Meng, Song, Ge, Beutler, Nathan, Shaabani, Namir, Huang, Deli, He, Wan-ting, Zhu, Xueyong, Callaghan, Sean, Yong, Peter, Anzanello, Fabio, Peng, Linghang, Ricketts, James, Parren, Mara, Garcia, Elijah, Rawlings, Stephen A., Smith, Davey M., Nemazee, David, Teijaro, John R., Rogers, Thomas F., Wilson, Ian A., Burton, Dennis R., Andrabi, Raiees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020973/
https://www.ncbi.nlm.nih.gov/pubmed/33821273
http://dx.doi.org/10.1101/2021.03.30.437769
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