Severity of SARS-CoV-2 infection as a function of the interferon landscape across the respiratory tract of COVID-19 patients.

The COVID-19 outbreak driven by SARS-CoV-2 has caused more than 2.5 million deaths globally, with the most severe cases characterized by over-exuberant production of immune-mediators, the nature of which is not fully understood. Interferons of the type I (IFN-I) or type III (IFN-III) families are po...

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Detalles Bibliográficos
Autores principales: Sposito, Benedetta, Broggi, Achille, Pandolfi, Laura, Crotta, Stefania, Ferrarese, Roberto, Sisti, Sofia, Clementi, Nicola, Ambrosi, Alessandro, Liu, Enju, Frangipane, Vanessa, Saracino, Laura, Marongiu, Laura, Facchini, Fabio A, Bottazzi, Andrea, Fossali, Tommaso, Colombo, Riccardo, Clementi, Massimo, Tagliabue, Elena, Pontiroli, Antonio E, Meloni, Federica, Wack, Andreas, Mancini, Nicasio, Zanoni, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020981/
https://www.ncbi.nlm.nih.gov/pubmed/33821280
http://dx.doi.org/10.1101/2021.03.30.437173

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