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Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19
The novel SARS-CoV-2 virus emerged in December 2019 and has few effective treatments. We applied a computational drug repositioning pipeline to SARS-CoV-2 differential gene expression signatures derived from publicly available data. We utilized three independent published studies to acquire or gener...
Autores principales: | Le, Brian L., Andreoletti, Gaia, Oskotsky, Tomiko, Vallejo-Gracia, Albert, Rosales, Romel, Yu, Katharine, Kosti, Idit, Leon, Kristoffer E., Bunis, Daniel G., Li, Christine, Kumar, G. Renuka, White, Kris M., García-Sastre, Adolfo, Ott, Melanie, Sirota, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020993/ https://www.ncbi.nlm.nih.gov/pubmed/33821262 http://dx.doi.org/10.21203/rs.3.rs-333578/v1 |
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