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Gender Differences on Methadone Maintenance Treatment Outcome among Patients with Opioid use Disorder: A Systematic Review

OBJECTIVES: The objective of this study was to review the significant differences of MMT outcomes related to drug use behavior, health status, and social behavioral functioning between genders. MATERIALS AND METHODS: A search of publication was conducted in PubMed/MEDLINE, Embase, CINAHL, PsycINFO,...

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Autores principales: Mohemmad Rizal, Mohemmad Redzuan, Hayat Khan, Amer, Noor Harun, Sabariah, Saleh, Zaiton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021040/
https://www.ncbi.nlm.nih.gov/pubmed/33828356
http://dx.doi.org/10.4103/jpbs.JPBS_253_19
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author Mohemmad Rizal, Mohemmad Redzuan
Hayat Khan, Amer
Noor Harun, Sabariah
Saleh, Zaiton
author_facet Mohemmad Rizal, Mohemmad Redzuan
Hayat Khan, Amer
Noor Harun, Sabariah
Saleh, Zaiton
author_sort Mohemmad Rizal, Mohemmad Redzuan
collection PubMed
description OBJECTIVES: The objective of this study was to review the significant differences of MMT outcomes related to drug use behavior, health status, and social behavioral functioning between genders. MATERIALS AND METHODS: A search of publication was conducted in PubMed/MEDLINE, Embase, CINAHL, PsycINFO, and Scopus database. Two reviewers independently screened the titles, abstracts, and keyword use for the search. Inclusion of studies was based on randomized controlled trials (RCTs) or observational studies that report the difference of opioid addiction treatment outcomes between genders. Any conflict between the two reviewers was resolved through discussion and consensus. The systematic review followed the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines and was registered in PROSPERO with a registration number CRD42019116261. RESULTS: A total of 25 studies were evaluated as part of qualitative synthesis. The review resulted in three main themes, which are (1) improving well-being and methadone-related outcome (five subthemes), (2) impact on social and behavioral (four subthemes), and (3) illicit drug use pattern–related behavior (four subthemes). CONCLUSION: This review will highlight how men and women differ in methadone treatment outcomes for further application and improvement in the clinical setting.
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spelling pubmed-80210402021-04-06 Gender Differences on Methadone Maintenance Treatment Outcome among Patients with Opioid use Disorder: A Systematic Review Mohemmad Rizal, Mohemmad Redzuan Hayat Khan, Amer Noor Harun, Sabariah Saleh, Zaiton J Pharm Bioallied Sci Review Article OBJECTIVES: The objective of this study was to review the significant differences of MMT outcomes related to drug use behavior, health status, and social behavioral functioning between genders. MATERIALS AND METHODS: A search of publication was conducted in PubMed/MEDLINE, Embase, CINAHL, PsycINFO, and Scopus database. Two reviewers independently screened the titles, abstracts, and keyword use for the search. Inclusion of studies was based on randomized controlled trials (RCTs) or observational studies that report the difference of opioid addiction treatment outcomes between genders. Any conflict between the two reviewers was resolved through discussion and consensus. The systematic review followed the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines and was registered in PROSPERO with a registration number CRD42019116261. RESULTS: A total of 25 studies were evaluated as part of qualitative synthesis. The review resulted in three main themes, which are (1) improving well-being and methadone-related outcome (five subthemes), (2) impact on social and behavioral (four subthemes), and (3) illicit drug use pattern–related behavior (four subthemes). CONCLUSION: This review will highlight how men and women differ in methadone treatment outcomes for further application and improvement in the clinical setting. Wolters Kluwer - Medknow 2020-11 2020-11-05 /pmc/articles/PMC8021040/ /pubmed/33828356 http://dx.doi.org/10.4103/jpbs.JPBS_253_19 Text en Copyright: © 2020 Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Mohemmad Rizal, Mohemmad Redzuan
Hayat Khan, Amer
Noor Harun, Sabariah
Saleh, Zaiton
Gender Differences on Methadone Maintenance Treatment Outcome among Patients with Opioid use Disorder: A Systematic Review
title Gender Differences on Methadone Maintenance Treatment Outcome among Patients with Opioid use Disorder: A Systematic Review
title_full Gender Differences on Methadone Maintenance Treatment Outcome among Patients with Opioid use Disorder: A Systematic Review
title_fullStr Gender Differences on Methadone Maintenance Treatment Outcome among Patients with Opioid use Disorder: A Systematic Review
title_full_unstemmed Gender Differences on Methadone Maintenance Treatment Outcome among Patients with Opioid use Disorder: A Systematic Review
title_short Gender Differences on Methadone Maintenance Treatment Outcome among Patients with Opioid use Disorder: A Systematic Review
title_sort gender differences on methadone maintenance treatment outcome among patients with opioid use disorder: a systematic review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021040/
https://www.ncbi.nlm.nih.gov/pubmed/33828356
http://dx.doi.org/10.4103/jpbs.JPBS_253_19
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