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Medication Adherence Assessment Among Patients with Type 2 Diabetes Mellitus Treated Polytherapy in Indonesian Community Health Center: A Cross Sectional-Study

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic disease where most of the patients usually need polytherapy. This could affect their medication adherence (MA). However, other complex factors may also associate with MA, which are important to identify. AIM: The purpose of this study was to e...

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Autores principales: Wulandari, Nora, Maifitrianti, Maifitrianti, Hasanah, Faridlatul, Atika, Sri, Dini Putri, Risa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021045/
https://www.ncbi.nlm.nih.gov/pubmed/33828374
http://dx.doi.org/10.4103/jpbs.JPBS_257_19
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author Wulandari, Nora
Maifitrianti, Maifitrianti
Hasanah, Faridlatul
Atika, Sri
Dini Putri, Risa
author_facet Wulandari, Nora
Maifitrianti, Maifitrianti
Hasanah, Faridlatul
Atika, Sri
Dini Putri, Risa
author_sort Wulandari, Nora
collection PubMed
description BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic disease where most of the patients usually need polytherapy. This could affect their medication adherence (MA). However, other complex factors may also associate with MA, which are important to identify. AIM: The purpose of this study was to evaluate the MA of patients with T2DM who received polytherapy and to identify other factors that can affect the MA. MATERIALS AND METHODS: This was a cross-sectional study conducted in seven community health centers in Jakarta with HbA(1C) representing their MA level. Poor controlled blood glucose with Hemoglobin A(1C) (HbA(1C)) of ≥7% is indicated to have low MA. All characteristics were collected to identify factors that are potentially associated with low MA. The univariate analysis tests were used to analyze factors that potentially associate with low MA. Multiple logistic regression analysis was performed in the factors to find their relationship with low MA. RESULTS: The study obtained 143 patients with a female dominance (67.8%) and mean ± standard deviation (SD) age of 59.53 ± 9.251 years. Approximately 75.5% of the patients had low MA (HbA(1C) ≥ 7). Univariate analysis found that duration of T2DM significantly (P = 0.047) related to MA, where patients with T2DM of less than or equal to 5 years tended to have low MA. Logistic regression showed that patients with T2DM less than or equal to 5 years (P = 0.015, odds ratio = 1.206, 95% confidence interval = 1.216–8.014) were associated with low MA. CONCLUSION: Patients with the duration of T2DM less than or equal to 5 years surprisingly were susceptible to have low MA. Low MA was not affected by polytherapy.
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spelling pubmed-80210452021-04-06 Medication Adherence Assessment Among Patients with Type 2 Diabetes Mellitus Treated Polytherapy in Indonesian Community Health Center: A Cross Sectional-Study Wulandari, Nora Maifitrianti, Maifitrianti Hasanah, Faridlatul Atika, Sri Dini Putri, Risa J Pharm Bioallied Sci Original Article BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic disease where most of the patients usually need polytherapy. This could affect their medication adherence (MA). However, other complex factors may also associate with MA, which are important to identify. AIM: The purpose of this study was to evaluate the MA of patients with T2DM who received polytherapy and to identify other factors that can affect the MA. MATERIALS AND METHODS: This was a cross-sectional study conducted in seven community health centers in Jakarta with HbA(1C) representing their MA level. Poor controlled blood glucose with Hemoglobin A(1C) (HbA(1C)) of ≥7% is indicated to have low MA. All characteristics were collected to identify factors that are potentially associated with low MA. The univariate analysis tests were used to analyze factors that potentially associate with low MA. Multiple logistic regression analysis was performed in the factors to find their relationship with low MA. RESULTS: The study obtained 143 patients with a female dominance (67.8%) and mean ± standard deviation (SD) age of 59.53 ± 9.251 years. Approximately 75.5% of the patients had low MA (HbA(1C) ≥ 7). Univariate analysis found that duration of T2DM significantly (P = 0.047) related to MA, where patients with T2DM of less than or equal to 5 years tended to have low MA. Logistic regression showed that patients with T2DM less than or equal to 5 years (P = 0.015, odds ratio = 1.206, 95% confidence interval = 1.216–8.014) were associated with low MA. CONCLUSION: Patients with the duration of T2DM less than or equal to 5 years surprisingly were susceptible to have low MA. Low MA was not affected by polytherapy. Wolters Kluwer - Medknow 2020-11 2020-11-05 /pmc/articles/PMC8021045/ /pubmed/33828374 http://dx.doi.org/10.4103/jpbs.JPBS_257_19 Text en Copyright: © 2020 Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Wulandari, Nora
Maifitrianti, Maifitrianti
Hasanah, Faridlatul
Atika, Sri
Dini Putri, Risa
Medication Adherence Assessment Among Patients with Type 2 Diabetes Mellitus Treated Polytherapy in Indonesian Community Health Center: A Cross Sectional-Study
title Medication Adherence Assessment Among Patients with Type 2 Diabetes Mellitus Treated Polytherapy in Indonesian Community Health Center: A Cross Sectional-Study
title_full Medication Adherence Assessment Among Patients with Type 2 Diabetes Mellitus Treated Polytherapy in Indonesian Community Health Center: A Cross Sectional-Study
title_fullStr Medication Adherence Assessment Among Patients with Type 2 Diabetes Mellitus Treated Polytherapy in Indonesian Community Health Center: A Cross Sectional-Study
title_full_unstemmed Medication Adherence Assessment Among Patients with Type 2 Diabetes Mellitus Treated Polytherapy in Indonesian Community Health Center: A Cross Sectional-Study
title_short Medication Adherence Assessment Among Patients with Type 2 Diabetes Mellitus Treated Polytherapy in Indonesian Community Health Center: A Cross Sectional-Study
title_sort medication adherence assessment among patients with type 2 diabetes mellitus treated polytherapy in indonesian community health center: a cross sectional-study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021045/
https://www.ncbi.nlm.nih.gov/pubmed/33828374
http://dx.doi.org/10.4103/jpbs.JPBS_257_19
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