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KLF11 protects against abdominal aortic aneurysm through inhibition of endothelial cell dysfunction

Abdominal aortic aneurysm (AAA) is a life-threatening degenerative vascular disease. Endothelial cell (EC) dysfunction is implicated in AAA. Our group recently demonstrated that Krüppel-like factor 11 (KLF11) plays an essential role in maintaining vascular homeostasis, at least partially through inh...

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Detalles Bibliográficos
Autores principales: Zhao, Guizhen, Chang, Ziyi, Zhao, Yang, Guo, Yanhong, Lu, Haocheng, Liang, Wenying, Rom, Oren, Wang, Huilun, Sun, Jinjian, Zhu, Tianqing, Fan, Yanbo, Chang, Lin, Yang, Bo, Garcia-Barrio, Minerva T., Chen, Y. Eugene, Zhang, Jifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021107/
https://www.ncbi.nlm.nih.gov/pubmed/33507881
http://dx.doi.org/10.1172/jci.insight.141673