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PDLIM2 repression by ROS in alveolar macrophages promotes lung tumorigenesis

One of the most fundamental and challenging questions in the field of cancer is how immunity is transformed from tumor immunosurveillance to tumor-promoting inflammation. Here, we identified the tumor suppressor PDZ-LIM domain–containing protein 2 (PDLIM2) as a checkpoint of alveolar macrophages (AM...

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Detalles Bibliográficos
Autores principales:	Li, Liwen, Sun, Fan, Han, Lei, Liu, Xujie, Xiao, Yadong, Gregory, Alyssa D., Shapiro, Steven D., Xiao, Gutian, Qu, Zhaoxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021114/ https://www.ncbi.nlm.nih.gov/pubmed/33539325 http://dx.doi.org/10.1172/jci.insight.144394

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