Epithelial miR-141 regulates IL-13–induced airway mucus production

IL-13–induced goblet cell metaplasia contributes to airway remodeling and pathological mucus hypersecretion in asthma. miRNAs are potent modulators of cellular responses, but their role in mucus regulation is largely unexplored. We hypothesized that airway epithelial miRNAs play roles in IL-13–induc...

Descripción completa

Detalles Bibliográficos
Autores principales: Siddiqui, Sana, Johansson, Kristina, Joo, Alex, Bonser, Luke R., Koh, Kyung Duk, Le Tonqueze, Olivier, Bolourchi, Samaneh, Bautista, Rodriel A., Zlock, Lorna, Roth, Theodore L., Marson, Alexander, Bhakta, Nirav R., Ansel, K. Mark, Finkbeiner, Walter E., Erle, David J., Woodruff, Prescott G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021117/
https://www.ncbi.nlm.nih.gov/pubmed/33682796
http://dx.doi.org/10.1172/jci.insight.139019

Ejemplares similares

Ejemplares similares