Cargando…
TLR2-mediated activation of innate responses in the upper airways confers antiviral protection of the lungs
The impact of respiratory virus infections on global health is felt not just during a pandemic, but endemic seasonal infections pose an equal and ongoing risk of severe disease. Moreover, vaccines and antiviral drugs are not always effective or available for many respiratory viruses. We investigated...
Autores principales: | Deliyannis, Georgia, Wong, Chinn Yi, McQuilten, Hayley A., Bachem, Annabell, Clarke, Michele, Jia, Xiaoxiao, Horrocks, Kylie, Zeng, Weiguang, Girkin, Jason, Scott, Nichollas E., Londrigan, Sarah L., Reading, Patrick C., Bartlett, Nathan W., Kedzierska, Katherine, Brown, Lorena E., Mercuri, Francesca, Demaison, Christophe, Jackson, David C., Chua, Brendon Y. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021123/ https://www.ncbi.nlm.nih.gov/pubmed/33561017 http://dx.doi.org/10.1172/jci.insight.140267 |
Ejemplares similares
-
Immature Brain Cortical Neurons Have Low Transcriptional Competence to Activate Antiviral Defences and Control RNA Virus Infections
por: Narayanan, Divya, et al.
Publicado: (2022) -
Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude
por: Quinn, Kylie M., et al.
Publicado: (2017) -
Anticoagulation in COVID-19
por: Bradbury, Charlotte A, et al.
Publicado: (2022) -
TRIM16 Overexpression in HEK293T Cells Results in Cell Line-Specific Antiviral Activity
por: Nigos, Lance R., et al.
Publicado: (2023) -
Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model
por: Proud, Pamela C., et al.
Publicado: (2020)