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Amino Acid Conjugates of Aminothiazole and Aminopyridine as Potential Anticancer Agents: Synthesis, Molecular Docking and in vitro Evaluation

PURPOSE: The development of resistance to available anticancer drugs is increasingly becoming a major challenge and new chemical entities could be unveiled to compensate this therapeutic failure. The current study demonstrated the synthesis of 2-aminothiazole [S3(a-d) and S5(a-d)] and 2-aminopyridin...

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Detalles Bibliográficos
Autores principales: Naz, Shagufta, Shah, Fawad Ali, Nadeem, Humaira, Sarwar, Sadia, Tan, Zhen, Imran, Muhammad, Ali, Tahir, Li, Jing Bo, Li, Shupeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021256/
https://www.ncbi.nlm.nih.gov/pubmed/33833504
http://dx.doi.org/10.2147/DDDT.S297013