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The role of mechanical control of biofilm in the salivary pH after sucrose exposure in children with early childhood caries
This quasi-experimental study sought to investigate if the mechanical control of biofilm (3-times-a-day) modifies the saliva’s ability to buffer the oral environment after 20% sucrose rinse (SR(20%)) in children with early childhood caries (ECC). Here, SR(20%) reduced the saliva’s pH in both groups...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021547/ https://www.ncbi.nlm.nih.gov/pubmed/33820926 http://dx.doi.org/10.1038/s41598-021-86861-4 |
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author | Lima-Holanda, Aline Tavares de Sousa, Emerson Tavares Nobre-dos-Santos, Marinês Steiner-Oliveira, Carolina |
author_facet | Lima-Holanda, Aline Tavares de Sousa, Emerson Tavares Nobre-dos-Santos, Marinês Steiner-Oliveira, Carolina |
author_sort | Lima-Holanda, Aline Tavares |
collection | PubMed |
description | This quasi-experimental study sought to investigate if the mechanical control of biofilm (3-times-a-day) modifies the saliva’s ability to buffer the oral environment after 20% sucrose rinse (SR(20%)) in children with early childhood caries (ECC). Here, SR(20%) reduced the saliva’s pH in both groups and the mechanical control of biofilm had a greater effect on this parameter after SR(20%) in CF children. The mechanical control of biofilm evidenced a higher buffering capacity in CF children before SR(20%), which was not observed after SR(20%). Otherwise, the absence of mechanical control of biofilm showed that buffering capacity was comparable in the two groups before SR(20%), whereas after SR(20%) the saliva’s buffering capacity of CF children was higher than ECC children. When biofilm was mechanically controlled, carbonic anhydrase VI activity did not change after SR(20%) whereas the absence of mechanical control of biofilm reduced this enzyme activity after SR(20%). In conclusion, the mechanical control of biofilm did not change saliva’s ability to buffer the oral environment after SR(20%) in children with ECC. On the other hand, CF children appeared to regulate more effectively the saliva’s pH than ECC children while the absence of mechanical control of biofilm mediated their pH-modifying ability after SR(20%). |
format | Online Article Text |
id | pubmed-8021547 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-80215472021-04-07 The role of mechanical control of biofilm in the salivary pH after sucrose exposure in children with early childhood caries Lima-Holanda, Aline Tavares de Sousa, Emerson Tavares Nobre-dos-Santos, Marinês Steiner-Oliveira, Carolina Sci Rep Article This quasi-experimental study sought to investigate if the mechanical control of biofilm (3-times-a-day) modifies the saliva’s ability to buffer the oral environment after 20% sucrose rinse (SR(20%)) in children with early childhood caries (ECC). Here, SR(20%) reduced the saliva’s pH in both groups and the mechanical control of biofilm had a greater effect on this parameter after SR(20%) in CF children. The mechanical control of biofilm evidenced a higher buffering capacity in CF children before SR(20%), which was not observed after SR(20%). Otherwise, the absence of mechanical control of biofilm showed that buffering capacity was comparable in the two groups before SR(20%), whereas after SR(20%) the saliva’s buffering capacity of CF children was higher than ECC children. When biofilm was mechanically controlled, carbonic anhydrase VI activity did not change after SR(20%) whereas the absence of mechanical control of biofilm reduced this enzyme activity after SR(20%). In conclusion, the mechanical control of biofilm did not change saliva’s ability to buffer the oral environment after SR(20%) in children with ECC. On the other hand, CF children appeared to regulate more effectively the saliva’s pH than ECC children while the absence of mechanical control of biofilm mediated their pH-modifying ability after SR(20%). Nature Publishing Group UK 2021-04-05 /pmc/articles/PMC8021547/ /pubmed/33820926 http://dx.doi.org/10.1038/s41598-021-86861-4 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Lima-Holanda, Aline Tavares de Sousa, Emerson Tavares Nobre-dos-Santos, Marinês Steiner-Oliveira, Carolina The role of mechanical control of biofilm in the salivary pH after sucrose exposure in children with early childhood caries |
title | The role of mechanical control of biofilm in the salivary pH after sucrose exposure in children with early childhood caries |
title_full | The role of mechanical control of biofilm in the salivary pH after sucrose exposure in children with early childhood caries |
title_fullStr | The role of mechanical control of biofilm in the salivary pH after sucrose exposure in children with early childhood caries |
title_full_unstemmed | The role of mechanical control of biofilm in the salivary pH after sucrose exposure in children with early childhood caries |
title_short | The role of mechanical control of biofilm in the salivary pH after sucrose exposure in children with early childhood caries |
title_sort | role of mechanical control of biofilm in the salivary ph after sucrose exposure in children with early childhood caries |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021547/ https://www.ncbi.nlm.nih.gov/pubmed/33820926 http://dx.doi.org/10.1038/s41598-021-86861-4 |
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