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A new open-access platform for measuring and sharing mTBI data

Despite numerous research efforts, the precise mechanisms of concussion have yet to be fully uncovered. Clinical studies on high-risk populations, such as contact sports athletes, have become more common and give insight on the link between impact severity and brain injury risk through the use of we...

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Autores principales: Domel, August G., Raymond, Samuel J., Giordano, Chiara, Liu, Yuzhe, Yousefsani, Seyed Abdolmajid, Fanton, Michael, Cecchi, Nicholas J., Vovk, Olga, Pirozzi, Ileana, Kight, Ali, Avery, Brett, Boumis, Athanasia, Fetters, Tyler, Jandu, Simran, Mehring, William M., Monga, Sam, Mouchawar, Nicole, Rangel, India, Rice, Eli, Roy, Pritha, Sami, Sohrab, Singh, Heer, Wu, Lyndia, Kuo, Calvin, Zeineh, Michael, Grant, Gerald, Camarillo, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021549/
https://www.ncbi.nlm.nih.gov/pubmed/33820939
http://dx.doi.org/10.1038/s41598-021-87085-2
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author Domel, August G.
Raymond, Samuel J.
Giordano, Chiara
Liu, Yuzhe
Yousefsani, Seyed Abdolmajid
Fanton, Michael
Cecchi, Nicholas J.
Vovk, Olga
Pirozzi, Ileana
Kight, Ali
Avery, Brett
Boumis, Athanasia
Fetters, Tyler
Jandu, Simran
Mehring, William M.
Monga, Sam
Mouchawar, Nicole
Rangel, India
Rice, Eli
Roy, Pritha
Sami, Sohrab
Singh, Heer
Wu, Lyndia
Kuo, Calvin
Zeineh, Michael
Grant, Gerald
Camarillo, David B.
author_facet Domel, August G.
Raymond, Samuel J.
Giordano, Chiara
Liu, Yuzhe
Yousefsani, Seyed Abdolmajid
Fanton, Michael
Cecchi, Nicholas J.
Vovk, Olga
Pirozzi, Ileana
Kight, Ali
Avery, Brett
Boumis, Athanasia
Fetters, Tyler
Jandu, Simran
Mehring, William M.
Monga, Sam
Mouchawar, Nicole
Rangel, India
Rice, Eli
Roy, Pritha
Sami, Sohrab
Singh, Heer
Wu, Lyndia
Kuo, Calvin
Zeineh, Michael
Grant, Gerald
Camarillo, David B.
author_sort Domel, August G.
collection PubMed
description Despite numerous research efforts, the precise mechanisms of concussion have yet to be fully uncovered. Clinical studies on high-risk populations, such as contact sports athletes, have become more common and give insight on the link between impact severity and brain injury risk through the use of wearable sensors and neurological testing. However, as the number of institutions operating these studies grows, there is a growing need for a platform to share these data to facilitate our understanding of concussion mechanisms and aid in the development of suitable diagnostic tools. To that end, this paper puts forth two contributions: (1) a centralized, open-access platform for storing and sharing head impact data, in collaboration with the Federal Interagency Traumatic Brain Injury Research informatics system (FITBIR), and (2) a deep learning impact detection algorithm (MiGNet) to differentiate between true head impacts and false positives for the previously biomechanically validated instrumented mouthguard sensor (MiG2.0), all of which easily interfaces with FITBIR. We report 96% accuracy using MiGNet, based on a neural network model, improving on previous work based on Support Vector Machines achieving 91% accuracy, on an out of sample dataset of high school and collegiate football head impacts. The integrated MiG2.0 and FITBIR system serve as a collaborative research tool to be disseminated across multiple institutions towards creating a standardized dataset for furthering the knowledge of concussion biomechanics.
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spelling pubmed-80215492021-04-07 A new open-access platform for measuring and sharing mTBI data Domel, August G. Raymond, Samuel J. Giordano, Chiara Liu, Yuzhe Yousefsani, Seyed Abdolmajid Fanton, Michael Cecchi, Nicholas J. Vovk, Olga Pirozzi, Ileana Kight, Ali Avery, Brett Boumis, Athanasia Fetters, Tyler Jandu, Simran Mehring, William M. Monga, Sam Mouchawar, Nicole Rangel, India Rice, Eli Roy, Pritha Sami, Sohrab Singh, Heer Wu, Lyndia Kuo, Calvin Zeineh, Michael Grant, Gerald Camarillo, David B. Sci Rep Article Despite numerous research efforts, the precise mechanisms of concussion have yet to be fully uncovered. Clinical studies on high-risk populations, such as contact sports athletes, have become more common and give insight on the link between impact severity and brain injury risk through the use of wearable sensors and neurological testing. However, as the number of institutions operating these studies grows, there is a growing need for a platform to share these data to facilitate our understanding of concussion mechanisms and aid in the development of suitable diagnostic tools. To that end, this paper puts forth two contributions: (1) a centralized, open-access platform for storing and sharing head impact data, in collaboration with the Federal Interagency Traumatic Brain Injury Research informatics system (FITBIR), and (2) a deep learning impact detection algorithm (MiGNet) to differentiate between true head impacts and false positives for the previously biomechanically validated instrumented mouthguard sensor (MiG2.0), all of which easily interfaces with FITBIR. We report 96% accuracy using MiGNet, based on a neural network model, improving on previous work based on Support Vector Machines achieving 91% accuracy, on an out of sample dataset of high school and collegiate football head impacts. The integrated MiG2.0 and FITBIR system serve as a collaborative research tool to be disseminated across multiple institutions towards creating a standardized dataset for furthering the knowledge of concussion biomechanics. Nature Publishing Group UK 2021-04-05 /pmc/articles/PMC8021549/ /pubmed/33820939 http://dx.doi.org/10.1038/s41598-021-87085-2 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Domel, August G.
Raymond, Samuel J.
Giordano, Chiara
Liu, Yuzhe
Yousefsani, Seyed Abdolmajid
Fanton, Michael
Cecchi, Nicholas J.
Vovk, Olga
Pirozzi, Ileana
Kight, Ali
Avery, Brett
Boumis, Athanasia
Fetters, Tyler
Jandu, Simran
Mehring, William M.
Monga, Sam
Mouchawar, Nicole
Rangel, India
Rice, Eli
Roy, Pritha
Sami, Sohrab
Singh, Heer
Wu, Lyndia
Kuo, Calvin
Zeineh, Michael
Grant, Gerald
Camarillo, David B.
A new open-access platform for measuring and sharing mTBI data
title A new open-access platform for measuring and sharing mTBI data
title_full A new open-access platform for measuring and sharing mTBI data
title_fullStr A new open-access platform for measuring and sharing mTBI data
title_full_unstemmed A new open-access platform for measuring and sharing mTBI data
title_short A new open-access platform for measuring and sharing mTBI data
title_sort new open-access platform for measuring and sharing mtbi data
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021549/
https://www.ncbi.nlm.nih.gov/pubmed/33820939
http://dx.doi.org/10.1038/s41598-021-87085-2
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