Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease

DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a key member of the phosphatidylinositol-3 kinase-like (PIKK) family of protein kinases with critical roles in DNA-double strand break repair, transcription, metastasis, mitosis, RNA processing, and innate and adaptive immunity. The absenc...

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Detalles Bibliográficos
Autores principales: Lees-Miller, James P., Cobban, Alexander, Katsonis, Panagiotis, Bacolla, Albino, Tsutakawa, Susan E., Hammel, Michal, Meek, Katheryn, Anderson, Dave W., Lichtarge, Olivier, Tainer, John A., Lees-Miller, Susan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021618/
https://www.ncbi.nlm.nih.gov/pubmed/33035590
http://dx.doi.org/10.1016/j.pbiomolbio.2020.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021618/
https://www.ncbi.nlm.nih.gov/pubmed/33035590
http://dx.doi.org/10.1016/j.pbiomolbio.2020.09.010

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