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Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease

DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a key member of the phosphatidylinositol-3 kinase-like (PIKK) family of protein kinases with critical roles in DNA-double strand break repair, transcription, metastasis, mitosis, RNA processing, and innate and adaptive immunity. The absenc...

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Detalles Bibliográficos
Autores principales:	Lees-Miller, James P., Cobban, Alexander, Katsonis, Panagiotis, Bacolla, Albino, Tsutakawa, Susan E., Hammel, Michal, Meek, Katheryn, Anderson, Dave W., Lichtarge, Olivier, Tainer, John A., Lees-Miller, Susan P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021618/ https://www.ncbi.nlm.nih.gov/pubmed/33035590 http://dx.doi.org/10.1016/j.pbiomolbio.2020.09.010

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