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Hypothesis and Theory: Roles of Arginine Methylation in C9orf72-Mediated ALS and FTD
Hexanucleotide repeat expansion (G4C2(n)) mutations in the gene C9ORF72 account for approximately 30% of familial cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), as well as approximately 7% of sporadic cases of ALS. G4C2(n) mutations are known to result in the product...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021787/ https://www.ncbi.nlm.nih.gov/pubmed/33833668 http://dx.doi.org/10.3389/fncel.2021.633668 |