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Nicotinamide Mononucleotide Attenuates Renal Interstitial Fibrosis After AKI by Suppressing Tubular DNA Damage and Senescence
Acute kidney injury (AKI) is a worldwide health problem currently lacking therapeutics that directly promote renal repair or prevent the occurrence of chronic fibrosis. DNA damage is a feature of many forms of kidney injury, and targeting DNA damage and repair might be effective strategies for kidne...
Autores principales: | Jia, Yan, Kang, Xin, Tan, Lishan, Ren, Yifei, Qu, Lei, Tang, Jiawei, Liu, Gang, Wang, Suxia, Xiong, Zuying, Yang, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021789/ https://www.ncbi.nlm.nih.gov/pubmed/33833691 http://dx.doi.org/10.3389/fphys.2021.649547 |
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