Profiles of 5α-Reduced Androgens in Humans and Eels: 5α-Dihydrotestosterone and 11-Ketodihydrotestosterone Are Active Androgens Produced in Eel Gonads

Although 11-ketotestosterone (11KT) and testosterone (T) are major androgens in both teleosts and humans, their 5α-reduced derivatives produced by steroid 5α-reductase (SRD5A/srd5a), i.e., 11-ketodihydrotestosterone (11KDHT) and 5α-dihydrotestosterone (DHT), remains poorly characterized, especially...

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Detalles Bibliográficos
Autores principales: Yazawa, Takashi, Inaba, Hiroyuki, Imamichi, Yoshitaka, Sekiguchi, Toshio, Uwada, Junsuke, Islam, Mohammad Sayful, Orisaka, Makoto, Mikami, Daisuke, Ida, Takanori, Sato, Takahiro, Miyashiro, Yoshimichi, Takahashi, Satoru, Khan, Md. Rafiqul Islam, Suzuki, Nobuo, Umezawa, Akihiro, Kitano, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021924/
https://www.ncbi.nlm.nih.gov/pubmed/33833737
http://dx.doi.org/10.3389/fendo.2021.657360

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