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Antifibrotic Effect of a Novel Selective 11β-HSD2 Inhibitor (WZ51) in a rat Model of Myocardial Fibrosis

Myocardial fibrosis (MF) is one of the leading causes of end-stage heart disease. Many studies have confirmed that inflammation caused by aldosterone may play an important role in the process of MF. A selective 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) enzyme inhibitor can reduce the inacti...

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Detalles Bibliográficos
Autores principales:	Zhuang, Fei, Ge, Qin, Qian, Jianchang, Wang, Zhe, Dong, Yaoyao, Chen, Mengchun, Zhang, Xiaodan, Sun, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022133/ https://www.ncbi.nlm.nih.gov/pubmed/33833680 http://dx.doi.org/10.3389/fphar.2021.629818

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