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Complement-5 Inhibition Deters Progression of Fulminant Hepatitis to Acute Liver Failure in Murine Models

BACKGROUND & AIMS: Acute liver failure (ALF) is a life-threatening condition with limited treatment alternatives. ALF pathogenesis seemingly involves the complement system. However, no complement-targeted intervention has been clinically applied. In this study, we aimed to investigate the potent...

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Detalles Bibliográficos
Autores principales:	Kusakabe, Jiro, Hata, Koichiro, Miyauchi, Hidetaka, Tajima, Tetsuya, Wang, Yi, Tamaki, Ichiro, Kawasoe, Junya, Okamura, Yusuke, Zhao, Xiangdong, Okamoto, Tatsuya, Tsuruyama, Tatsuaki, Uemoto, Shinji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022253/ https://www.ncbi.nlm.nih.gov/pubmed/33444818 http://dx.doi.org/10.1016/j.jcmgh.2021.01.001

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