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Dexmedetomidine attenuates myocardial ischemia-reperfusion injury in vitro by inhibiting NLRP3 Inflammasome activation

BACKGROUND: Myocardial ischemia-reperfusion injury (MIRI) is the most common cause of death worldwide. The NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome plays an important role in the inflammatory response to MIRI. Dexmedetomidine (DEX), a specific agonist of α2-adrenergic re...

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Detalles Bibliográficos
Autores principales:	Huang, Yaru, Sun, Xiaotong, Juan, Zhaodong, Zhang, Rui, Wang, Ruoguo, Meng, Shuqi, Zhou, Jiajia, Li, Yan, Xu, Keyou, Xie, Keliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022424/ https://www.ncbi.nlm.nih.gov/pubmed/33823789 http://dx.doi.org/10.1186/s12871-021-01334-5

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