Reduced replication fork speed promotes pancreatic endocrine differentiation and controls graft size

Limitations in cell proliferation are important for normal function of differentiated tissues and essential for the safety of cell replacement products made from pluripotent stem cells, which have unlimited proliferative potential. To evaluate whether these limitations can be established pharmacolog...

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Detalles Bibliográficos
Autores principales: Sui, Lina, Xin, Yurong, Du, Qian, Georgieva, Daniela, Diedenhofen, Giacomo, Haataja, Leena, Su, Qi, Zuccaro, Michael V., Kim, Jinrang, Fu, Jiayu, Xing, Yuan, He, Yi, Baum, Danielle, Goland, Robin S., Wang, Yong, Oberholzer, Jose, Barbetti, Fabrizio, Arvan, Peter, Kleiner, Sandra, Egli, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022502/
https://www.ncbi.nlm.nih.gov/pubmed/33529174
http://dx.doi.org/10.1172/jci.insight.141553

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