Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD

BACKGROUND: Whole lung tissue transcriptomic profiling studies in chronic obstructive pulmonary disease (COPD) have led to the identification of several genes associated with the severity of airflow limitation and/or the presence of emphysema, however, the cell types driving these gene expression si...

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Detalles Bibliográficos
Autores principales: Li, Xiuying, Noell, Guillaume, Tabib, Tracy, Gregory, Alyssa D., Trejo Bittar, Humberto E., Vats, Ravi, Kaminski, Tomasz W., Sembrat, John, Snyder, Mark E., Chandra, Divay, Chen, Kong, Zou, Chunbin, Zhang, Yingze, Sundd, Prithu, McDyer, John F., Sciurba, Frank, Rojas, Mauricio, Lafyatis, Robert, Shapiro, Steve D., Faner, Rosa, Nyunoya, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022543/
https://www.ncbi.nlm.nih.gov/pubmed/33823868
http://dx.doi.org/10.1186/s12931-021-01675-2

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