Chemotherapy-elicited exosomal miR-378a-3p and miR-378d promote breast cancer stemness and chemoresistance via the activation of EZH2/STAT3 signaling

BACKGROUND: Not all breast cancer (BC) patients who receive neoadjuvant chemotherapy achieve a pathologic complete response (pCR), but the reasons for this are unknown. Previous studies have shown that exosomes produced in the tumor microenvironment in response to chemotherapy promote a chemotherapy...

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Detalles Bibliográficos
Autores principales: Yang, Qianxi, Zhao, Shaorong, Shi, Zhendong, Cao, Lixia, Liu, Jingjing, Pan, Teng, Zhou, Dongdong, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022546/
https://www.ncbi.nlm.nih.gov/pubmed/33823894
http://dx.doi.org/10.1186/s13046-021-01901-1

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