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Novel therapies emerging in oncology to target the TGF-β pathway

The TGF-β signaling pathway governs key cellular processes under physiologic conditions and is deregulated in many pathologies, including cancer. TGF-β is a multifunctional cytokine that acts in a cell- and context-dependent manner as a tumor promoter or tumor suppressor. As a tumor promoter, the TG...

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Detalles Bibliográficos
Autores principales:	Kim, Byung-Gyu, Malek, Ehsan, Choi, Sung Hee, Ignatz-Hoover, James J., Driscoll, James J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022551/ https://www.ncbi.nlm.nih.gov/pubmed/33823905 http://dx.doi.org/10.1186/s13045-021-01053-x

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