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Acetylation of NDUFV1 induced by a newly synthesized HDAC6 inhibitor HGC rescues dopaminergic neuron loss in Parkinson models

It has been shown that histone deacetylase (HDAC) inhibitors hold considerable therapeutic potentials for treating neurodegeneration-related diseases including Parkinson disease (PD). Here, we synthesized an HDAC inhibitor named as HGC and examined its neuroprotective roles in PD models. Our results...

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Detalles Bibliográficos
Autores principales:	Li, Bing, Yang, Yinuo, Wang, Yuejun, Zhang, Jing, Ding, Jie, Liu, Xiaoyu, Jin, Yan, Lian, Bolin, Ling, Yong, Sun, Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022854/ https://www.ncbi.nlm.nih.gov/pubmed/33851105 http://dx.doi.org/10.1016/j.isci.2021.102302

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