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Discovery of bone morphogenetic protein 7-derived peptide sequences that attenuate the human osteoarthritic chondrocyte phenotype

Treatment of osteoarthritis (OA) is mainly symptomatic by alleviating pain to postpone total joint replacement. Bone morphogenetic protein 7 (BMP7) is a candidate morphogen for experimental OA treatment that favorably alters the chondrocyte and cartilage phenotype. Intra-articular delivery and susta...

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Detalles Bibliográficos
Autores principales:	Caron, Marjolein M.J., Ripmeester, Ellen G.J., van den Akker, Guus, Wijnands, Nina K.A. P., Steijns, Jessica, Surtel, Don A.M., Cremers, Andy, Emans, Pieter J., van Rhijn, Lodewijk W., Welting, Tim J.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022858/ https://www.ncbi.nlm.nih.gov/pubmed/33850953 http://dx.doi.org/10.1016/j.omtm.2021.03.009

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