Investigating Mechanisms of Response or Resistance to Immune Checkpoint Inhibitors by Analyzing Cell-Cell Communications in Tumors Before and After Programmed Cell Death-1 (PD-1) Targeted Therapy: An Integrative Analysis Using Single-cell RNA and Bulk-RNA Sequencing Data

Currently, a significant proportion of cancer patients do not benefit from programmed cell death-1 (PD-1)-targeted therapy. Overcoming drug resistance remains a challenge. In this study, single-cell RNA sequencing and bulk RNA sequencing data from samples collected before and after anti-PD-1 therapy...

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Detalles Bibliográficos
Autores principales: Jiang, Yi-Quan, Wang, Zi-Xian, Zhong, Ming, Shen, Lu-Jun, Han, Xue, Zou, Xuxiazi, Liu, Xin-Yi, Deng, Yi-Nan, Yang, Yang, Chen, Gui-Hua, Deng, Wuguo, Huang, Jin-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023241/
https://www.ncbi.nlm.nih.gov/pubmed/33868792
http://dx.doi.org/10.1080/2162402X.2021.1908010

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