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Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype
In malaria-naïve children and adults, Plasmodium falciparum-infected red blood cells (Pf-iRBCs) trigger fever and other symptoms of systemic inflammation. However, in endemic areas where individuals experience repeated Pf infections over many years, the risk of Pf-iRBC-triggered inflammatory symptom...
Autores principales: | Guha, Rajan, Mathioudaki, Anna, Doumbo, Safiatou, Doumtabe, Didier, Skinner, Jeff, Arora, Gunjan, Siddiqui, Shafiuddin, Li, Shanping, Kayentao, Kassoum, Ongoiba, Aissata, Zaugg, Judith, Traore, Boubacar, Crompton, Peter D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023468/ https://www.ncbi.nlm.nih.gov/pubmed/33822828 http://dx.doi.org/10.1371/journal.ppat.1009430 |
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