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The capacity of origins to load MCM establishes replication timing patterns
Loading of the MCM replicative helicase at origins of replication is a highly regulated process that precedes DNA replication in all eukaryotes. The stoichiometry of MCM loaded at origins has been proposed to be a key determinant of when those origins initiate replication during S phase. Nevertheles...
Autores principales: | Dukaj, Livio, Rhind, Nicholas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023499/ https://www.ncbi.nlm.nih.gov/pubmed/33764973 http://dx.doi.org/10.1371/journal.pgen.1009467 |
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