Electromembrane Extraction and Mass Spectrometry for Liver Organoid Drug Metabolism Studies

[Image: see text] Liver organoids are emerging tools for precision drug development and toxicity screening. We demonstrate that electromembrane extraction (EME) based on electrophoresis across an oil membrane is suited for segregating selected organoid-derived drug metabolites prior to mass spectrom...

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Detalles Bibliográficos
Autores principales: Skottvoll, Frøydis Sved, Hansen, Frederik André, Harrison, Sean, Boger, Ida Sneis, Mrsa, Ago, Restan, Magnus Saed, Stein, Matthias, Lundanes, Elsa, Pedersen-Bjergaard, Stig, Aizenshtadt, Aleksandra, Krauss, Stefan, Sullivan, Gareth, Bogen, Inger Lise, Wilson, Steven Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023518/
https://www.ncbi.nlm.nih.gov/pubmed/33534551
http://dx.doi.org/10.1021/acs.analchem.0c05082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023518/
https://www.ncbi.nlm.nih.gov/pubmed/33534551
http://dx.doi.org/10.1021/acs.analchem.0c05082

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