Cargando…

Electromembrane Extraction and Mass Spectrometry for Liver Organoid Drug Metabolism Studies

[Image: see text] Liver organoids are emerging tools for precision drug development and toxicity screening. We demonstrate that electromembrane extraction (EME) based on electrophoresis across an oil membrane is suited for segregating selected organoid-derived drug metabolites prior to mass spectrom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Skottvoll, Frøydis Sved, Hansen, Frederik André, Harrison, Sean, Boger, Ida Sneis, Mrsa, Ago, Restan, Magnus Saed, Stein, Matthias, Lundanes, Elsa, Pedersen-Bjergaard, Stig, Aizenshtadt, Aleksandra, Krauss, Stefan, Sullivan, Gareth, Bogen, Inger Lise, Wilson, Steven Ray
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023518/ https://www.ncbi.nlm.nih.gov/pubmed/33534551 http://dx.doi.org/10.1021/acs.analchem.0c05082

Ejemplares similares

“Organ-in-a-Column” Coupled On-line with Liquid Chromatography-Mass Spectrometry
por: Kogler, Stian, et al.
Publicado: (2022)

Electromembrane Extraction Using Sacrificial Electrodes
por: Hansen, Frederik A., et al.
Publicado: (2020)

Investigating Monoliths (Vinyl Azlactone-co-Ethylene Dimethacrylate) as a Support for Enzymes and Drugs, for Proteomics and Drug-Target Studies
por: Olsen, Christine, et al.
Publicado: (2019)

Electromembrane extraction–Recent trends and where to go
por: Pedersen-Bjergaard, Stig, et al.
Publicado: (2017)

Quantitative chemometric phenotyping of three-dimensional liver organoids by Raman spectral imaging
por: LaLone, Vernon, et al.
Publicado: (2023)

Generic Liquid Membranes for Electromembrane Extraction of Bases with Low or Moderate Hydrophilicity
por: Zhou, Chen, et al.
Publicado: (2023)

Conductive vial electromembrane extraction of opioids from oral fluid
por: Skaalvik, Tonje Gottenberg, et al.
Publicado: (2023)

Ultracentrifugation versus kit exosome isolation: nanoLC–MS and other tools reveal similar performance biomarkers, but also contaminations
por: Skottvoll, Frøydis Sved, et al.
Publicado: (2018)

Electromembrane Processes: Experiments and Modelling
por: Gurreri, Luigi, et al.
Publicado: (2021)

Environmental Applications of Electromembrane Extraction: A Review
por: Shi, Linping, et al.
Publicado: (2023)

Scalable production of tissue-like vascularized liver organoids from human PSCs
por: Harrison, Sean P., et al.
Publicado: (2023)

Electroextraction and electromembrane extraction: Advances in hyphenation to analytical techniques
por: Oedit, Amar, et al.
Publicado: (2016)

Desalination of Neutral Amino Acid Solutions in an Electromembrane System
por: Eliseeva, Tatiana, et al.
Publicado: (2022)

Theoretical Investigation of the Phenomenon of Space Charge Breakdown in Electromembrane Systems
por: Kovalenko, Anna, et al.
Publicado: (2022)

Preconcentration of Fluorescent Dyes in Electromembrane Systems via Electrophoretic Migration
por: Kim, Minsung, et al.
Publicado: (2023)

Analytical Performance of Electromembranes as a Tool for Nanoconcentrations of Silver in Waters
por: Silva, Macarena, et al.
Publicado: (2022)

Membrane Deformation and Its Effects on Flow and Mass Transfer in the Electromembrane Processes
por: Battaglia, Giuseppe, et al.
Publicado: (2019)

Electromembrane Extraction of Highly Polar Compounds: Analysis of Cardiovascular Biomarkers in Plasma
por: Drouin, Nicolas, et al.
Publicado: (2019)

Water Splitting and Transport of Ions in Electromembrane System with Bilayer Ion-Exchange Membrane
por: Melnikov, Stanislav, et al.
Publicado: (2020)

Mathematical Modeling of the Influence of the Karman Vortex Street on Mass Transfer in Electromembrane Systems
por: Uzdenova, Aminat, et al.
Publicado: (2023)

Electromembrane Extraction of Posaconazole for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Detection
por: Chen, Chi-Sheng, et al.
Publicado: (2022)

Mathematical Modeling of the Phenomenon of Space-Charge Breakdown in the Galvanostatic Mode in the Section of the Electromembrane Desalination Channel
por: Uzdenova, Aminat, et al.
Publicado: (2021)

Ion Transport and Process of Water Dissociation in Electromembrane System with Bipolar Membrane: Modelling of Symmetrical Case
por: Melnikov, Stanislav
Publicado: (2022)

Ion Transport in Electromembrane Systems under the Passage of Direct Current: 1D Modelling Approaches
por: Uzdenova, Aminat
Publicado: (2023)

Comparison of commercial nanoliquid chromatography columns for fast, targeted mass spectrometry-based proteomics
por: Vehus, Tore, et al.
Publicado: (2016)

Green Method for the Selective Electromembrane Extraction of Parabens and Fluoroquinolones in the Presence of NSAIDs by Using Biopolymeric Chitosan Films
por: Román-Hidalgo, Cristina, et al.
Publicado: (2023)

Programmable Millifluidic Platform Integrating Automatic Electromembrane Extraction Cleanup and In-Line Electrochemical Detection: A Proof of Concept
por: Sahragard, Ali, et al.
Publicado: (2022)

Correction to Programmable Millifluidic Platform Integrating Automatic Electromembrane Extraction Cleanup and In-Line Electrochemical Detection: A Proof of Concept
por: Sahragard, Ali, et al.
Publicado: (2023)

Open Tubular Lab-On-Column/Mass Spectrometry for Targeted Proteomics of Nanogram Sample Amounts
por: Hustoft, Hanne Kolsrud, et al.
Publicado: (2014)

Development of a β-cyclodextrin-modified gold nanoparticle-assisted electromembrane extraction method followed by capillary electrophoresis for methadone determination in plasma
por: Hoseininezhad-Namin, Mir Saleh, et al.
Publicado: (2022)

Erratum: Melnikov, S.; et al. Water Splitting and Transport of Ions in Electromembrane System with Bilayer Ion-Exchange Membrane. Membranes 2020, 10, 346
por: Melnikov, Stanislav, et al.
Publicado: (2020)

The Intrauterine and Nursing Period Is a Window of Susceptibility for Development of Obesity and Intestinal Tumorigenesis by a High Fat Diet in Min/+ Mice as Adults
por: Ngo, Ha Thi, et al.
Publicado: (2015)

Academic User View: Organ-on-a-Chip Technology
por: Busek, Mathias, et al.
Publicado: (2022)

Liquid chromatography-mass spectrometry platform for both small neurotransmitters and neuropeptides in blood, with automatic and robust solid phase extraction
por: Johnsen, Elin, et al.
Publicado: (2015)

Open Science in Closed Societies
por: Mrša, Vladimir
Publicado: (2020)

Openness and How to Stay ‘Open’
por: Mrša, Vladimir
Publicado: (2019)

Decreasing Costs of Dissemination of Research Results by Publishing in Diamond Open Access Journals
por: Mrša, Vladimir
Publicado: (2022)

Should we open the reviewing process
por: Mrša, Vladimir
Publicado: (2021)

Versatile, sensitive liquid chromatography mass spectrometry – Implementation of 10 μm OT columns suitable for small molecules, peptides and proteins
por: Vehus, T., et al.
Publicado: (2016)

Characterization of human stem cell-derived hepatic stellate cells and liver sinusoidal endothelial cells during extended in vitro culture
por: Wilhelmsen, Ingrid, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_krfb9ddsr0c00krrltpn0ir97r