Cargando…

Structural Mechanism of ω-Currents in a Mutated Kv7.2 Voltage Sensor Domain from Molecular Dynamics Simulations

[Image: see text] Activation of voltage-gated ion channels is regulated by conformational changes of the voltage sensor domains (VSDs), four water- and ion-impermeable modules peripheral to the central, permeable pore domain. Anomalous currents, defined as ω-currents, have been recorded in response...

Descripción completa

Detalles Bibliográficos
Autores principales: Alberini, Giulio, Benfenati, Fabio, Maragliano, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023575/
https://www.ncbi.nlm.nih.gov/pubmed/33570938
http://dx.doi.org/10.1021/acs.jcim.0c01407

Ejemplares similares