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glmGamPoi: fitting Gamma-Poisson generalized linear models on single cell count data

MOTIVATION: The Gamma-Poisson distribution is a theoretically and empirically motivated model for the sampling variability of single cell RNA-sequencing counts and an essential building block for analysis approaches including differential expression analysis, principal component analysis and factor...

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Detalles Bibliográficos
Autores principales: Ahlmann-Eltze, Constantin, Huber, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023675/
https://www.ncbi.nlm.nih.gov/pubmed/33295604
http://dx.doi.org/10.1093/bioinformatics/btaa1009

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