Identifying structural–functional analogue of GRL0617, the only well-established inhibitor for papain-like protease (PLpro) of SARS-CoV2 from the pool of fungal metabolites using docking and molecular dynamics simulation

ABSTRACT: The non-structural protein (nsp)-3 of SARS-CoV2 coronavirus is sought to be an essential target protein which is also named as papain-like protease (PLpro). This protease cleaves the viral polyprotein, but importantly in human host it also removes ubiquitin-like interferon-stimulated gene...

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Detalles Bibliográficos
Autores principales: Rao, Priyashi, Patel, Rohit, Shukla, Arpit, Parmar, Paritosh, Rawal, Rakesh M., Saraf, Meenu, Goswami, Dweipayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023777/
https://www.ncbi.nlm.nih.gov/pubmed/33825097
http://dx.doi.org/10.1007/s11030-021-10220-8

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