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Gold Nanocomposite Contact Lenses for Color Blindness Management
[Image: see text] Color vision deficiency (CVD) is an ocular congenital disorder that affects 8% of males and 0.5% of females. The most prevalent form of color vision deficiency (color blindness) affects protans and deutans and is more commonly known as “red–green color blindness”. Since there is no...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023801/ https://www.ncbi.nlm.nih.gov/pubmed/33570901 http://dx.doi.org/10.1021/acsnano.0c09657 |
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author | Salih, Ahmed E. Elsherif, Mohamed Alam, Fahad Yetisen, Ali K. Butt, Haider |
author_facet | Salih, Ahmed E. Elsherif, Mohamed Alam, Fahad Yetisen, Ali K. Butt, Haider |
author_sort | Salih, Ahmed E. |
collection | PubMed |
description | [Image: see text] Color vision deficiency (CVD) is an ocular congenital disorder that affects 8% of males and 0.5% of females. The most prevalent form of color vision deficiency (color blindness) affects protans and deutans and is more commonly known as “red–green color blindness”. Since there is no cure for this disorder, CVD patients opt for wearables that aid in enhancing their color perception. The most common wearable used by CVD patients is a form of tinted glass/lens. Those glasses filter out the problematic wavelengths (540–580 nm) for the red–green CVD patients using organic dyes. However, few studies have addressed the fabrication of contact lenses for color vision deficiency, and several problems related to their effectiveness and toxicity were reported. In this study, gold nanoparticles are integrated into contact lens material, thus forming nanocomposite contact lenses targeted for red–green CVD application. Three distinct sets of nanoparticles were characterized and incorporated with the hydrogel material of the lenses (pHEMA), and their resulting optical and material properties were assessed. The transmission spectra of the developed nanocomposite lenses were analogous to those of the commercial CVD wearables, and their water retention and wettability capabilities were superior to those in some of the commercially available contact lenses used for cosmetic/vision correction purposes. Hence, this work demonstrates the potential of gold nanocomposite lenses in CVD management and, more generally, color filtering applications. |
format | Online Article Text |
id | pubmed-8023801 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | American
Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-80238012021-04-07 Gold Nanocomposite Contact Lenses for Color Blindness Management Salih, Ahmed E. Elsherif, Mohamed Alam, Fahad Yetisen, Ali K. Butt, Haider ACS Nano [Image: see text] Color vision deficiency (CVD) is an ocular congenital disorder that affects 8% of males and 0.5% of females. The most prevalent form of color vision deficiency (color blindness) affects protans and deutans and is more commonly known as “red–green color blindness”. Since there is no cure for this disorder, CVD patients opt for wearables that aid in enhancing their color perception. The most common wearable used by CVD patients is a form of tinted glass/lens. Those glasses filter out the problematic wavelengths (540–580 nm) for the red–green CVD patients using organic dyes. However, few studies have addressed the fabrication of contact lenses for color vision deficiency, and several problems related to their effectiveness and toxicity were reported. In this study, gold nanoparticles are integrated into contact lens material, thus forming nanocomposite contact lenses targeted for red–green CVD application. Three distinct sets of nanoparticles were characterized and incorporated with the hydrogel material of the lenses (pHEMA), and their resulting optical and material properties were assessed. The transmission spectra of the developed nanocomposite lenses were analogous to those of the commercial CVD wearables, and their water retention and wettability capabilities were superior to those in some of the commercially available contact lenses used for cosmetic/vision correction purposes. Hence, this work demonstrates the potential of gold nanocomposite lenses in CVD management and, more generally, color filtering applications. American Chemical Society 2021-02-11 2021-03-23 /pmc/articles/PMC8023801/ /pubmed/33570901 http://dx.doi.org/10.1021/acsnano.0c09657 Text en © 2021 American Chemical Society Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Salih, Ahmed E. Elsherif, Mohamed Alam, Fahad Yetisen, Ali K. Butt, Haider Gold Nanocomposite Contact Lenses for Color Blindness Management |
title | Gold
Nanocomposite Contact Lenses for Color Blindness
Management |
title_full | Gold
Nanocomposite Contact Lenses for Color Blindness
Management |
title_fullStr | Gold
Nanocomposite Contact Lenses for Color Blindness
Management |
title_full_unstemmed | Gold
Nanocomposite Contact Lenses for Color Blindness
Management |
title_short | Gold
Nanocomposite Contact Lenses for Color Blindness
Management |
title_sort | gold
nanocomposite contact lenses for color blindness
management |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023801/ https://www.ncbi.nlm.nih.gov/pubmed/33570901 http://dx.doi.org/10.1021/acsnano.0c09657 |
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