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Transglutaminase 2 Depletion Attenuates α-Synuclein Mediated Toxicity in Mice
α-Synuclein (α-Syn) is a key pathogenic protein in α-synucleinopathies including Parkinson disease (PD) and Dementia with Lewy Bodies. The aggregation of α-Syn is believed to be deleterious and a critical step leading to neuronal dysfunction and death. One of the factors that may contribute to the i...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024061/ https://www.ncbi.nlm.nih.gov/pubmed/32502569 http://dx.doi.org/10.1016/j.neuroscience.2020.05.047 |