Cargando…
Rational design of flavonoid based potential inhibitors targeting SARS-CoV 3CL protease for the treatment of COVID-19
The current outbreak of Coronavirus Disease 2019 (COVID-19) pandemic has reported thousands of deaths worldwide due to the rapid transmission rate and the lack of antiviral drugs and vaccinations. There is an urgent need to develop potential antiviral drug candidates for the prevention of COVID-19 i...
Autores principales: | Bhati, Shipra, Kaushik, Vikas, Singh, Joginder |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024110/ https://www.ncbi.nlm.nih.gov/pubmed/33840835 http://dx.doi.org/10.1016/j.molstruc.2021.130380 |
Ejemplares similares
-
Inhibition of SARS-CoV 3CL protease by flavonoids
por: Jo, Seri, et al.
Publicado: (2019) -
Structure-based drug designing of naphthalene based SARS-CoV PLpro inhibitors for the treatment of COVID-19
por: Bhati, Shipra
Publicado: (2020) -
Design, synthesis, and evaluation of trifluoromethyl ketones as inhibitors of SARS-CoV 3CL protease
por: Shao, Yi-Ming, et al.
Publicado: (2008) -
Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease
por: Su, Haixia, et al.
Publicado: (2021) -
Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors
por: Iketani, Sho, et al.
Publicado: (2020)